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Research.
Harnessing evolution's designs.
Selected works
Preprint2026Co-first authorA Noncontiguous Code for RNA-Guided DNA Recognition Preceded CRISPRVIPR · RNA-guided DNA recognition · phage defensePreprint2026Shown rotatingTriplex formation drives noncontiguous VIPR RNA-guided DNA recognitionVIPR structure · RNA-guided DNA recognitionNature2025A miniature CRISPR-Cas10 enzyme confers immunity by an inverse signaling pathwayimmune signaling · bacterial defense · toxin-antitoxin systemsScience2024Structure-guided discovery of ancestral CRISPR-Cas13 ribonucleasesRNA-guided RNase · structural homology · Cas13 ancestryNucleic Acids Research2023Eukaryotic RNA-guided endonucleases evolved from a unique clade of bacterial enzymestransposons · RNA-guided endonuclease
About.
Grew up on Frank Herbert, Ted Chiang, and my grandmother's gong sik chaau min under the Southern California Sun.
Probably somewhere flipping rocks.